Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer


NCT00860691

Interventional

N/A

Unknown status
The purpose of this study is: - to determine neutrophil activity in patients with colon cancer, - to determine levels sFas, sFasL and IL - 17 in serum of healthy volunteers and colon cancer patients and establish its prognostic value, - to elucidate the relationship between serum sFas, sFasL and IL - 17 levels and clinicopathologic features of colon cancer, - to compare the influence of laparoscopic and conventional procedures on postoperative serum sFas and sFasL levels in colon cancer patients - to compare the influence of laparoscopic and conventional procedures on postoperative serum IL - 17 levels in colon cancer patients - to compare the influence of laparoscopic and conventional procedures on postoperative neutrophil functions - to confirm the expression of FasL protein in human colorectal cancer and elucidate the relationship between FasL expression and clinicopathologic features of the disease, to establish the prevalence of Fas in primary colon adenocarcinomas and elucidate the relationship between FasL expression and clinicopathologic features of the disease - to determine the functional activity of tumour infiltrating neutrophils
Jan 31,2008
All
20 Years
80 Years
60

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